Epinum Cream (Lidocaine + Prilocaine)  Effective Topical Anesthetic Cream

Description:

Epinum Cream is a topical anesthetic cream formulated with Lidocaine and Prilocaine. This eutectic mixture remains in liquid form due to its low melting point, offering efficient pain relief

Composition:

 Each gram contains
Lidocaine USP 25 mg (2.5% w/w)

 Prilocaine USP 25 mg
(2.5% w/w)

 Pharmacodynamics:

•  Lidocaine and Prilocaine provide dermal anesthesia by inhibiting pain receptors and nerve endings
•  Maximal anesthesia is achieved after 12 hours of application, varying by skin location
•  Effective for needle procedures, laser treatment, and curettage of molluscum contagiosum in pediatric patients
•  Safe and efficacious for adult and elderly populations
•  Application to the genital mucosa achieves rapid anesthesia (1520 minutes)
•  Leg ulcers cleansing is achieved after 30 minutes of application
•  No need for dose reduction in hepatic or renal impairment
• Infants under 37 weeks gestational age should not use it due to the risk of methemoglobinemia.

 Warnings and Precautions:

•  Avoid use in patients with hypersensitivity to lidocaine, prilocaine, or related compounds
•  Exercise caution in patients with glucose6phosphate dehydrogenase deficiency and atopic dermatitis
•  Prolonged application on atopic dermatitis may cause local vascular reactions
•  Be cautious when applying near the eyes and rinse immediately if contact occurs
• Monitoring is necessary for patients on class I antiarrhythmics as their cardiac effects may accumulate.
•  Lidocaine and prilocaine have bactericidal and antiviral properties at concentrations above
  0.52%

 Use in Specific Populations:

•  Effective in pediatric patients for various procedures
•  Safe for the elderly population
• Hepatic or renal impairment does not require dosage adjustments.

 Epinum Cream provides effective pain relief for a wide range of procedures and patient populations. It is a valuable addition to dermatological and medical practices for local anesthesia